英文名(míng)稱：Scopoletin
CAS號(hào)：92-61-5
分析(xī)標(biāo)準品,≥98%
分子式 C10H8O4 分子量(liáng)192.17

基(jī)本信(xìn)息(xī):

密度1.377
熔點 200-207°C
描述(shù)
產品介紹(shào) 微(wēi)溶(róng)於(yú)水或冷(lěng)乙醇，溶於熱(rè)乙(yǐ)醇或熱冰(bīng)醋酸，易溶於(yú)氯(lǜ)仿，幾乎(hū)不(bù)溶(róng)於苯
。醇(chún)溶(róng)液呈(chéng)藍(lán)色(sè)熒光，還(huán)原(yuán)斐林氏溶液
。稀水溶(róng)液(yè)呈(chéng)藍(lán)色熒(yíng)光(guāng)，加入濃氨水(shuǐ)後熒(yíng)光增強，存(cún)在於茄科(kē)植物(wù)東(dōng)莨(làng)菪(Swpolia japonica Maxim.)根，顛茄(qié)(Atropa balladonna L.)，傘形科植(zhí)物(wù)興(xīng)安白(bái)芷(Angelica dahurica Benth. et Hook.)根(gēn)等中(zhōng)
。
別(bié)名 東莨菪內酯(zhǐ);東莨(làng)菪素;7-羥基-6-甲氧基香(xiāng)豆素;7-羥基-6-甲(jiǎ)氧(yǎng)基(jī)-2H-1-苯(běn)並吡(pǐ)喃(nán)-2-酮(tóng);6-甲氧(yǎng)基傘形酮;七(qī)葉(yè)亭-6-甲(jiǎ)醚;柯(kē)阿托酸(suān);鉤吻(wěn)酸;6-Methoxyumbelliferone; 7-Hydroxy-5-methoxycoumarin; 7-Hydroxy-6-methoxy-2H-1-benzopyran-2-one; Chrysatropic acid; Esculetin-6-methyl ether; Gelseminic acid; 7-Hydroxy-6-methoxycoumarin
生化機(jī)理 Dye that can be used to detect the release of reactive oxygen species during the oxidative burst; peroxynitrite scavenger; acetylcholinesterase inhibitor.Scopoletin significantly increases activity of lipoprotein lipase in adipocytes by promoting transcription of the LPL gene. It also partially reverses inhibition of LPL by TNF-α.
應用 染(rǎn)料，可用(yòng)於檢測(cè)氧(yǎng)化爆(bào)發期(qī)間(jiān)的活(huó)性(xìng)氧(yǎng)釋(shì)放;過氧清(qīng)道夫(fū);乙(yǐ)酰(xiān)膽鹼酯酶抑(yì)製劑
。
臨床上有(yǒu)祛(qū)風(fēng)，抗炎(yán)，止(zhǐ)痛，祛(qū)痰(tán)作用
。