產(chǎn)品(pǐn)中(zhōng)心(xīn)
標(biāo)記一抗
英文(wén)名稱Anti-ATP5B/FITC
中文(wén)名(míng)稱:FITC標記(jì)的(dí)ATP合成酶β5抗體
別(bié) 名ATP 5B; ATP synthase H+ transporting mitochondrial F1 complex beta polypeptide; ATP Synthase H+ Transporting Mitochondrial F1 Complex Subunit Beta; ATP synthase subunit beta mitochondrial; ATP synthase subunit beta, mitochondrial; ATP5B; ATPB; ATPB_HUMAN; ATPMB; ATPSB; MGC5231; Mitochondrial ATP synthase beta subunit; Mitochondrial ATP Synthase Subunit Beta; Mitochondrial ATP synthetase beta subunit.
規格:100ul
說 明(míng) 書(shū)100ul
研究領域(yù)腫瘤 細胞生物 免疫學(xué) 信(xìn)號轉導 轉錄調(tiáo)節因子
抗體(tǐ)來(lái)源Rabbit
克隆(lóng)類型Polyclonal
交(jiāo)叉(chā)反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
產(chǎn)品(pǐn)應用(yòng)ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量51kDa
細胞(bāo)定位(wèi)細胞(bāo)膜
性 狀Lyophilized or Liquid
濃(nóng) 度1mg/ml
免(miǎn) 疫 原KLH conjugated synthetic peptide derived from human ATP5B
亞(yà) 型(xíng)IgG
純化方(fāng)法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存(cún)條(tiáo)件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹(shào)background:
Mitochondrial ATP synthase is composed of two multi-subunit complexes that utilize an inner membrane electrochemical gradient to catalyze the synthesis of ATP during oxidative phosphorylation. The two multi-subunit complexes are designated F1 and F0, the former of which comprises the soluble catalytic core and the latter of which comprises the membrane-spanning proton channel of ATP synthase. F1 consists of five distinct subunits, designated ATP5A, ATP5B, ATP5C1, ATP5D and ATP5E, while F0 consists of ten subunits, designated ATP5H, ATP5G1, ATP5I, ATP5G2, ATP5J2, ATP5J, ATP5G3, ATP5S, ATP5F1 and ATP5L. ATP5B, also designated ATPMB, ATPSB or mitochondrial ATP synthetase, beta subunit, is a 529 amino acid protein that localizes to the mitochondrial membrane and exists as a subunit of the F0 complex. ATP5B is encoded by a nuclear gene and assembled with the other subunits encoded by both mitochondrial and nuclear genes. The ATP5B gene is activated by members of the Ets family of transcription factors, suggesting that Ets transcription factors are involved in the enhanced expression of the ATP5B gene in highly proliferating cells and in the coordinate transcription of nuclear genes for mitochondrial proteins. ATP5B mRNA levels vary among species through transcriptional control with high expression levels in heart, lower levels in skeletal muscle and the lowest levels in liver and kidney.
Function:
May play a role in melanocortin signaling pathways that regulate energy homeostasis.
Subunit:
Interacts with MC4R
Subcellular Location:
Membrane; Single-pass type I membrane protein
中文(wén)名(míng)稱:FITC標記(jì)的(dí)ATP合成酶β5抗體
別(bié) 名ATP 5B; ATP synthase H+ transporting mitochondrial F1 complex beta polypeptide; ATP Synthase H+ Transporting Mitochondrial F1 Complex Subunit Beta; ATP synthase subunit beta mitochondrial; ATP synthase subunit beta, mitochondrial; ATP5B; ATPB; ATPB_HUMAN; ATPMB; ATPSB; MGC5231; Mitochondrial ATP synthase beta subunit; Mitochondrial ATP Synthase Subunit Beta; Mitochondrial ATP synthetase beta subunit.
詳細(xì)介(jiè)紹：
規格:100ul
說 明(míng) 書(shū)100ul
研究領域(yù)腫瘤 細胞生物 免疫學(xué) 信(xìn)號轉導 轉錄調(tiáo)節因子
抗體(tǐ)來(lái)源Rabbit
克隆(lóng)類型Polyclonal
交(jiāo)叉(chā)反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
產(chǎn)品(pǐn)應用(yòng)ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量51kDa
細胞(bāo)定位(wèi)細胞(bāo)膜
性 狀Lyophilized or Liquid
濃(nóng) 度1mg/ml
免(miǎn) 疫 原KLH conjugated synthetic peptide derived from human ATP5B
亞(yà) 型(xíng)IgG
純化方(fāng)法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存(cún)條(tiáo)件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相關資料：
產品介紹(shào)background:
Mitochondrial ATP synthase is composed of two multi-subunit complexes that utilize an inner membrane electrochemical gradient to catalyze the synthesis of ATP during oxidative phosphorylation. The two multi-subunit complexes are designated F1 and F0, the former of which comprises the soluble catalytic core and the latter of which comprises the membrane-spanning proton channel of ATP synthase. F1 consists of five distinct subunits, designated ATP5A, ATP5B, ATP5C1, ATP5D and ATP5E, while F0 consists of ten subunits, designated ATP5H, ATP5G1, ATP5I, ATP5G2, ATP5J2, ATP5J, ATP5G3, ATP5S, ATP5F1 and ATP5L. ATP5B, also designated ATPMB, ATPSB or mitochondrial ATP synthetase, beta subunit, is a 529 amino acid protein that localizes to the mitochondrial membrane and exists as a subunit of the F0 complex. ATP5B is encoded by a nuclear gene and assembled with the other subunits encoded by both mitochondrial and nuclear genes. The ATP5B gene is activated by members of the Ets family of transcription factors, suggesting that Ets transcription factors are involved in the enhanced expression of the ATP5B gene in highly proliferating cells and in the coordinate transcription of nuclear genes for mitochondrial proteins. ATP5B mRNA levels vary among species through transcriptional control with high expression levels in heart, lower levels in skeletal muscle and the lowest levels in liver and kidney.
Function:
May play a role in melanocortin signaling pathways that regulate energy homeostasis.
Subunit:
Interacts with MC4R
Subcellular Location:
Membrane; Single-pass type I membrane protein
