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FITC標記的(dí)粘附分子IgG樣結構(gòu)域(yù)蛋(dàn)白(bái)1抗(kàng)體
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2017-5-2 瀏(liú)覽(lǎn)次數：1552
英(yīng)文名稱Anti-AMIGO1/FITC
中文名稱(chēng):FITC標(biāo)記(jì)的(dí)粘附(fù)分(fēn)子(zǐ)IgG樣(yàng)結構域蛋(dàn)白(bái)1抗(kàng)體
別(bié) 名(míng)Adhesion molecule with Ig like domain 1; ali2; Alivin 2; AMIGO 1; AMIGO; AMIGO protein; Amphoterin induced gene and ORF (Amigo); Amphoterin induced gene and ORF; Amphoterin induced protein 1; KIAA1163; AMGO1_HUMAN.
規(guī)格:100ul
說 明 書(shū)100ul
研(yán)究(jiū)領域神經(jīng)生(shēng)物(wù)學(xué) 信號轉(zhuǎn)導 細胞(bāo)粘附(fù)分子
抗體來源(yuán)Rabbit
克(kè)隆類(lèi)型Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
產品應(yīng)用(yòng)ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量(liáng)52kDa
細(xì)胞定(dìng)位(wèi)細(xì)胞膜
性 狀Lyophilized or Liquid
濃(nóng) 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human AMIGO1
亞(yà) 型(xíng)IgG
純化方(fāng)法affinity purified by Protein A
儲 存 液(yè)0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品(pǐn)介紹(shào)background:
The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO-1, AMIGO-2 and AMIGO-3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO-1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO-2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO-1 and AMIGO-2, AMIGO-3 (Alivin-3) plays a role in homophilic and/or heterophilic cell-cell interaction and signal transduction
Function:
AMIGO1 promotes growth and fasciculation of neurites from cultured hippocampal neurons. It may be involved in fasciculation as well as myelination of developing neural axons and have a role in regeneration as well as neural plasticity in the adult nervous system. AMIGO1 may also mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain.
Subunit:
Homodimer, and heterodimer with AMIGO2 and AMIGO3.
Subcellular Location:
Membrane; Single-pass type I membrane protein. Cell projection; axon. Note: Associated with axons of neuronal cells.
Similarity:
Belongs to the immunoglobulin superfamily. AMIGO family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 6 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.
Database links:
UniProtKB/Swiss-Prot: Q86WK6.1
中文名稱(chēng):FITC標(biāo)記(jì)的(dí)粘附(fù)分(fēn)子(zǐ)IgG樣(yàng)結構域蛋(dàn)白(bái)1抗(kàng)體
別(bié) 名(míng)Adhesion molecule with Ig like domain 1; ali2; Alivin 2; AMIGO 1; AMIGO; AMIGO protein; Amphoterin induced gene and ORF (Amigo); Amphoterin induced gene and ORF; Amphoterin induced protein 1; KIAA1163; AMGO1_HUMAN.
詳(xiáng)細介紹(shào)：
規(guī)格:100ul
說 明 書(shū)100ul
研(yán)究(jiū)領域神經(jīng)生(shēng)物(wù)學(xué) 信號轉(zhuǎn)導 細胞(bāo)粘附(fù)分子
抗體來源(yuán)Rabbit
克(kè)隆類(lèi)型Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
產品應(yīng)用(yòng)ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量(liáng)52kDa
細(xì)胞定(dìng)位(wèi)細(xì)胞膜
性 狀Lyophilized or Liquid
濃(nóng) 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human AMIGO1
亞(yà) 型(xíng)IgG
純化方(fāng)法affinity purified by Protein A
儲 存 液(yè)0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相關資(zī)料(liào)：
產(chǎn)品(pǐn)介紹(shào)background:
The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO-1, AMIGO-2 and AMIGO-3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO-1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO-2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO-1 and AMIGO-2, AMIGO-3 (Alivin-3) plays a role in homophilic and/or heterophilic cell-cell interaction and signal transduction
Function:
AMIGO1 promotes growth and fasciculation of neurites from cultured hippocampal neurons. It may be involved in fasciculation as well as myelination of developing neural axons and have a role in regeneration as well as neural plasticity in the adult nervous system. AMIGO1 may also mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain.
Subunit:
Homodimer, and heterodimer with AMIGO2 and AMIGO3.
Subcellular Location:
Membrane; Single-pass type I membrane protein. Cell projection; axon. Note: Associated with axons of neuronal cells.
Similarity:
Belongs to the immunoglobulin superfamily. AMIGO family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 6 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.
Database links:
UniProtKB/Swiss-Prot: Q86WK6.1
- 上一條(tiáo)：FITC標(biāo)記的β澱粉樣(yàng)前體蛋白(bái)結(jié)合(hé)蛋白3抗(kàng)體
- 下(xià)一條(tiáo)：FITC標記的(dí)星形(xíng)肌動蛋白抗(kàng)體
