產(chǎn)品中心(xīn)
標記一抗
FITC標(biāo)記的(dí)含(hán)錨蛋(dàn)白(bái)重復序列(liè)-細胞(bāo)因子信(xìn)號抑製物盒蛋(dàn)白家族(zú)7抗體(tǐ)
文字：[大(dà)][中(zhōng)][小]
2017-5-2 瀏覽(lǎn)次數(shù)：1497
英文名(míng)稱(chēng)Anti-ASB7/FITC
中文名稱:FITC標(biāo)記的(dí)含錨蛋(dàn)白(bái)重復序(xù)列-細胞(bāo)因(yīn)子(zǐ)信(xìn)號抑製(zhì)物盒蛋(dàn)白家(jiā)族7抗(kàng)體(tǐ)
別(bié) 名Ankyrin repeat and SOCS box containing protein 7; ASB 7; ASB-7; ASB7_HUMAN.
規格(gé):100ul
說 明 書(shū)100ul
研究領域細胞生物 免疫學(xué)
抗體來源Rabbit
克隆類型(xíng)Polyclonal
交叉(chā)反應 Human, Mouse, Rat, Chicken, Horse, Sheep,
產品應用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量(liáng)36kDa
性(xìng) 狀Lyophilized or Liquid
濃(nóng) 度(dù)1mg/ml
免(miǎn) 疫 原KLH conjugated synthetic peptide derived from human ASB7
亞 型(xíng)IgG
純(chún)化方(fāng)法affinity purified by Protein A
儲(chǔ) 存 液(yè)0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存條件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹(shào)background:
Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the Elongin B/C complex. Several other families of proteins also contain SOCS boxes, but differ from the SOCS proteins in the type of domain they contain upstream of the SOCS box. The largest family of SOCS box-containing proteins is the ankyrin repeat and SOCS box-containing (ASB) protein family. ASB-7 (ankyrin repeat and SOCS box-containing 7) is a 318 amino acid protein that contains one SOCS box domain and seven ANK repeats and belongs to the ASB family. Existing as multiple alternatively spliced isoforms, ASB-7 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins
Function:
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
Subunit:
Interacts with CUL5 and RNF7.
Similarity:
Contains 7 ANK repeats.
Contains 1 SOCS box domain.
Database links:
UniProtKB/Swiss-Prot: Q9H672.2
中文名稱:FITC標(biāo)記的(dí)含錨蛋(dàn)白(bái)重復序(xù)列-細胞(bāo)因(yīn)子(zǐ)信(xìn)號抑製(zhì)物盒蛋(dàn)白家(jiā)族7抗(kàng)體(tǐ)
別(bié) 名Ankyrin repeat and SOCS box containing protein 7; ASB 7; ASB-7; ASB7_HUMAN.
詳細介(jiè)紹(shào)：
規格(gé):100ul
說 明 書(shū)100ul
研究領域細胞生物 免疫學(xué)
抗體來源Rabbit
克隆類型(xíng)Polyclonal
交叉(chā)反應 Human, Mouse, Rat, Chicken, Horse, Sheep,
產品應用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量(liáng)36kDa
性(xìng) 狀Lyophilized or Liquid
濃(nóng) 度(dù)1mg/ml
免(miǎn) 疫 原KLH conjugated synthetic peptide derived from human ASB7
亞 型(xíng)IgG
純(chún)化方(fāng)法affinity purified by Protein A
儲(chǔ) 存 液(yè)0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存條件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相關(guān)資(zī)料(liào)：
產品介紹(shào)background:
Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the Elongin B/C complex. Several other families of proteins also contain SOCS boxes, but differ from the SOCS proteins in the type of domain they contain upstream of the SOCS box. The largest family of SOCS box-containing proteins is the ankyrin repeat and SOCS box-containing (ASB) protein family. ASB-7 (ankyrin repeat and SOCS box-containing 7) is a 318 amino acid protein that contains one SOCS box domain and seven ANK repeats and belongs to the ASB family. Existing as multiple alternatively spliced isoforms, ASB-7 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins
Function:
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
Subunit:
Interacts with CUL5 and RNF7.
Similarity:
Contains 7 ANK repeats.
Contains 1 SOCS box domain.
Database links:
UniProtKB/Swiss-Prot: Q9H672.2
