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標(biāo)記一抗(kàng)
英文名稱Anti-AER61/FITC
中(zhōng)文(wén)名稱:FITC標(biāo)記的未知(zhī)糖(táng)基化(huà)轉(zhuǎn)移酶AER61抗體(tǐ)
別 名(míng)C3orf64; Uncharacterized glycosyltransferase AER61; EOGT_HUMAN.
規(guī)格(gé):100ul
說(shuō) 明 書(shū)100ul
研究(jiū)領域(yù)細(xì)胞生物 免疫學(xué) 糖蛋(dàn)白
抗體來源Rabbit
克隆類(lèi)型Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
產品應(yīng)用(yòng)IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分(fēn) 子 量(liáng)60kDa
性 狀Lyophilized or Liquid
濃 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human AER61
亞 型(xíng)IgG
純(chún)化(huà)方法(fǎ)affinity purified by Protein A
儲 存 液(yè)0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存(cún)條(tiáo)件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介(jiè)紹background:
AER61 is a 527 amino acid secreted protein that belongs to the glycosyltransferase 61 family and exists as three alternatively spliced isoforms. C3orf64 is encoded by a gene mapping to human chromosome 3p14.1. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
Function:
Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like domains (By similarity).
Subcellular Location:
Endoplasmic reticulum lumen
Similarity:
Belongs to the glycosyltransferase 61 family.
中(zhōng)文(wén)名稱:FITC標(biāo)記的未知(zhī)糖(táng)基化(huà)轉(zhuǎn)移酶AER61抗體(tǐ)
別 名(míng)C3orf64; Uncharacterized glycosyltransferase AER61; EOGT_HUMAN.
詳細介紹(shào)：
規(guī)格(gé):100ul
說(shuō) 明 書(shū)100ul
研究(jiū)領域(yù)細(xì)胞生物 免疫學(xué) 糖蛋(dàn)白
抗體來源Rabbit
克隆類(lèi)型Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
產品應(yīng)用(yòng)IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分(fēn) 子 量(liáng)60kDa
性 狀Lyophilized or Liquid
濃 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human AER61
亞 型(xíng)IgG
純(chún)化(huà)方法(fǎ)affinity purified by Protein A
儲 存 液(yè)0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存(cún)條(tiáo)件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相關資料(liào)：
產品介(jiè)紹background:
AER61 is a 527 amino acid secreted protein that belongs to the glycosyltransferase 61 family and exists as three alternatively spliced isoforms. C3orf64 is encoded by a gene mapping to human chromosome 3p14.1. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
Function:
Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like domains (By similarity).
Subcellular Location:
Endoplasmic reticulum lumen
Similarity:
Belongs to the glycosyltransferase 61 family.
- 上一(yī)條(tiáo)：FITC標記的AGXT2L2蛋白抗(kàng)體(tǐ)
- 下一(yī)條(tiáo)：FITC標記的β澱粉(fěn)樣(yàng)蛋(dàn)白胞內結(jié)構(gòu)域相關蛋(dàn)白(bái)1抗(kàng)體
