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英(yīng)文(wén)名稱(chēng)Anti-A4GALT/FITC
中文(wén)名(míng)稱:FITC標(biāo)記的α1,4-半(bàn)乳糖基(jī)轉移(yí)酶(méi)1
別 名4 N acetylglucosaminyltransferase; 4-galactosyltransferase; 4-N-acetylglucosaminyltransferase; A14GALT; A4GALT; A4GALT1; A4GAT_HUMAN; Alpha 1 4 galactosyltransferase; Alpha 1 4 N acetylglucosaminyltransferase; Alpha-1; Alpha-1; Alpha4Gal T1; Alpha4Gal-T1; CD 77; CD77 synthase; GB3 synthase; Gb3S; Globotriaosylceramide synthase; Lactosylceramide 4 alpha galactosyltransferase; Lactosylceramide 4-alpha-galactosyltransferase; P blood group (P one antigen); P(k) antigen synthase; P1; P1/Pk synthase; PK; UDP galactose beta D galactosyl beta1 R 4 alpha D galactosyltransferase; UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase.
規(guī)格(gé):100ul
說(shuō) 明 書(shū)100ul
研究(jiū)領域(yù)心(xīn)血管(guǎn) 細胞生物(wù) 細胞表麵(miàn)分(fēn)子
抗(kàng)體來源Rabbit
克(kè)隆類型Polyclonal
交叉反(fǎn)應 Human, Mouse, Rat, Chicken, Dog, Pig,
產品應用(yòng)Flow-Cyt=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分(fēn) 子 量40kDa
細(xì)胞定位細胞膜(mó)
性 狀Lyophilized or Liquid
濃 度1mg/ml
免 疫(yì) 原(yuán)KLH conjugated synthetic peptide derived from human A4GALT/CD77
亞 型(xíng)IgG
純化(huà)方法(fǎ)affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存條(tiáo)件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹background:
Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins.Expression of CD77, also called Gb3, sensitizes a cell to verotoxins, causing cellular injury that can lead to disease. Therefore, the complex regulation of CD77 biosynthesis and the activity of the enzymes involved, such as CD77 synthase, can be studied by compared gene expression between toxin-sensitive and insensitive tissues and cell lines. The highest tissue expression of CD77 synthase occurs in the kidney, mesenteric lymph node, spleen, and brain. Burkitt leukemia cells express very high levels of CD77 as well as CD77 synthase, and are sensitive to verotoxin induced apoptosis. These megakaryoblasts then never mature, leading to the arrest of platelet generation in the bone marrow, which may cause thrombocytopenia, a symptom associated with various hemorrhagic conditions
中文(wén)名(míng)稱:FITC標(biāo)記的α1,4-半(bàn)乳糖基(jī)轉移(yí)酶(méi)1
別 名4 N acetylglucosaminyltransferase; 4-galactosyltransferase; 4-N-acetylglucosaminyltransferase; A14GALT; A4GALT; A4GALT1; A4GAT_HUMAN; Alpha 1 4 galactosyltransferase; Alpha 1 4 N acetylglucosaminyltransferase; Alpha-1; Alpha-1; Alpha4Gal T1; Alpha4Gal-T1; CD 77; CD77 synthase; GB3 synthase; Gb3S; Globotriaosylceramide synthase; Lactosylceramide 4 alpha galactosyltransferase; Lactosylceramide 4-alpha-galactosyltransferase; P blood group (P one antigen); P(k) antigen synthase; P1; P1/Pk synthase; PK; UDP galactose beta D galactosyl beta1 R 4 alpha D galactosyltransferase; UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase.
詳細介紹：
規(guī)格(gé):100ul
說(shuō) 明 書(shū)100ul
研究(jiū)領域(yù)心(xīn)血管(guǎn) 細胞生物(wù) 細胞表麵(miàn)分(fēn)子
抗(kàng)體來源Rabbit
克(kè)隆類型Polyclonal
交叉反(fǎn)應 Human, Mouse, Rat, Chicken, Dog, Pig,
產品應用(yòng)Flow-Cyt=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分(fēn) 子 量40kDa
細(xì)胞定位細胞膜(mó)
性 狀Lyophilized or Liquid
濃 度1mg/ml
免 疫(yì) 原(yuán)KLH conjugated synthetic peptide derived from human A4GALT/CD77
亞 型(xíng)IgG
純化(huà)方法(fǎ)affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存條(tiáo)件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相(xiāng)關資料(liào)：
產(chǎn)品介紹background:
Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins.Expression of CD77, also called Gb3, sensitizes a cell to verotoxins, causing cellular injury that can lead to disease. Therefore, the complex regulation of CD77 biosynthesis and the activity of the enzymes involved, such as CD77 synthase, can be studied by compared gene expression between toxin-sensitive and insensitive tissues and cell lines. The highest tissue expression of CD77 synthase occurs in the kidney, mesenteric lymph node, spleen, and brain. Burkitt leukemia cells express very high levels of CD77 as well as CD77 synthase, and are sensitive to verotoxin induced apoptosis. These megakaryoblasts then never mature, leading to the arrest of platelet generation in the bone marrow, which may cause thrombocytopenia, a symptom associated with various hemorrhagic conditions
- 上一(yī)條(tiáo)：FITC標(biāo)記的(dí)腺(xiàn)苷(gān)酸激酶2抗體
- 下一條(tiáo)：FITC標記(jì)的紅(hóng)細胞蛋(dàn)白(bái)Ank1抗(kàng)體
