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FITC標記的凋(diāo)亡蛋(dàn)白活(huó)性(xìng)因子(zǐ)1相(xiāng)互作(zuò)用(yòng)蛋白(bái)抗體(tǐ)
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2017-5-3 瀏覽(lǎn)次數(shù)：1556
英文名(míng)稱Anti-Apaf1 Interacting Protein/FITC
中文名(míng)稱:FITC標記的凋亡蛋白活(huó)性(xìng)因子1相(xiāng)互(hù)作用(yòng)蛋白(bái)抗(kàng)體
別 名(míng)MTNB_HUMAN; Apaf1 Interacting Protein; APIP2; CG129; CGI 29; MMRP19; MTRu 1 P dehydratase; Probable methylthioribulose 1 phosphate dehydratase.
規格:100ul
說 明 書(shū)100ul
研(yán)究領域(yù)細胞生(shēng)物 信號(hào)轉(zhuǎn)導 細胞凋亡(wáng)
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
產品應用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分(fēn) 子(zǐ) 量27kDa
性 狀Lyophilized or Liquid
濃(nóng) 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human APIP (178-225aa)
亞(yà) 型IgG
純化方法(fǎ)affinity purified by Protein A
儲 存(cún) 液(yè)0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存條(tiáo)件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品(pǐn)介(jiè)紹(shào)background:
The mammalian homologues of the key cell death gene CED 4 in C. elegans has been identified recently from human and mouse and designated Apaf1 (for apoptosis protease activating factor 1). Apaf1 binds to cytochrome c (Apaf2) and caspase 9 (Apaf3), which leads to caspase 9 activation. Activated caspase 9 in turn cleaves and activates caspase 3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. A new Apaf1 Interacting Protein (APIP) also known as CG129 and MMRP19, has been identified as a negative regulator of ischemic injury. APIP competes with Caspase 9 binding site of Apaf1. APIP is predicted to code for a 204 amino acid. An isoform of APIP, APIP2 encodes a 242 amino acid protein, which is an alternative splicing variant differing in its N terminus from APIP. APIP transcript is ubiquitously expressed in most adult tissue with high expression in skeletal muscle, heart, and kidney
中文名(míng)稱:FITC標記的凋亡蛋白活(huó)性(xìng)因子1相(xiāng)互(hù)作用(yòng)蛋白(bái)抗(kàng)體
別 名(míng)MTNB_HUMAN; Apaf1 Interacting Protein; APIP2; CG129; CGI 29; MMRP19; MTRu 1 P dehydratase; Probable methylthioribulose 1 phosphate dehydratase.
詳細介紹：
規格:100ul
說 明 書(shū)100ul
研(yán)究領域(yù)細胞生(shēng)物 信號(hào)轉(zhuǎn)導 細胞凋亡(wáng)
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
產品應用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分(fēn) 子(zǐ) 量27kDa
性 狀Lyophilized or Liquid
濃(nóng) 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human APIP (178-225aa)
亞(yà) 型IgG
純化方法(fǎ)affinity purified by Protein A
儲 存(cún) 液(yè)0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存條(tiáo)件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相(xiāng)關(guān)資(zī)料(liào)：
產品(pǐn)介(jiè)紹(shào)background:
The mammalian homologues of the key cell death gene CED 4 in C. elegans has been identified recently from human and mouse and designated Apaf1 (for apoptosis protease activating factor 1). Apaf1 binds to cytochrome c (Apaf2) and caspase 9 (Apaf3), which leads to caspase 9 activation. Activated caspase 9 in turn cleaves and activates caspase 3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. A new Apaf1 Interacting Protein (APIP) also known as CG129 and MMRP19, has been identified as a negative regulator of ischemic injury. APIP competes with Caspase 9 binding site of Apaf1. APIP is predicted to code for a 204 amino acid. An isoform of APIP, APIP2 encodes a 242 amino acid protein, which is an alternative splicing variant differing in its N terminus from APIP. APIP transcript is ubiquitously expressed in most adult tissue with high expression in skeletal muscle, heart, and kidney
- 上(shàng)一(yī)條(tiáo)：FITC標記(jì)的凋亡誘導(dǎo)因子(zǐ)3抗(kàng)體
- 下(xià)一(yī)條(tiáo)：FITC標(biāo)記的凋(diāo)亡誘導蛋(dàn)白(bái)D抗體
