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FITC標記的(dí)整(zhěng)合素(sù)樣金屬(shǔ)蛋(dàn)白酶(méi)與(yǔ)凝血酶(méi)樣(yàng)2蛋白(bái)抗(kàng)體(tǐ)
英文名(míng)稱(chēng)Anti-ADAMTSL2/FITC
中文(wén)名稱(chēng):FITC標(biāo)記(jì)的(dí)整(zhěng)合素樣(yàng)金(jīn)屬(shǔ)蛋(dàn)白酶(méi)與凝血酶樣(yàng)2蛋白(bái)抗體(tǐ)
別(bié) 名ADAMTS like 2; ADAMTS like protein 2; ADAMTS-like protein 2; ADAMTSL 2; ADAMTSL-2; ADAMTSL2; ATL2_HUMAN.
規格:100ul
說(shuō) 明 書(shū)100ul
研究(jiū)領(lǐng)域腫瘤(liú) 心血管 細胞(bāo)生物 免疫(yì)學 信(xìn)號(hào)轉導 生(shēng)長(cháng)因子和激素(sù) 細胞(bāo)粘附(fù)分(fēn)子
抗體(tǐ)來源Rabbit
克隆(lóng)類型(xíng)Polyclonal
交叉反(fǎn)應 Human, Mouse, Rat,
產品應(yīng)用(yòng)IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子(zǐ) 量102kDa
性 狀Lyophilized or Liquid
濃(nóng) 度1mg/ml
免 疫 原(yuán)KLH conjugated synthetic peptide derived from human ADAMTSL2
亞(yà) 型IgG
純化方(fāng)法(fǎ)affinity purified by Protein A
儲 存(cún) 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條(tiáo)件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹background:
ADAMTS (A Disintegrin And Metalloproteinase Domain with Thrombospondin type 1 Modules) is a family of zinc-dependent proteases that are implicated in a variety of normal and pathological conditions, including arthritis and cancer. ADAMTS protein family members contain an amino-terminal propeptide domain, a metalloproteinase domain, a disintegrin-like domain and a carboxy-terminus that contains a varying number of Thrombospondin type 1 (TSP-1) motifs. ADAMTS-L2 (ADAMTS-like protein 2) is a 951 amino acid secreted protein that is highly expressed in lung, kidney and liver. Mutations in the gene encoding ADAMTS are the cause of geleophysic dysplasia, an autosomal recessive disorder characterized by cardiac vavular anomalies, short stature, thick skin and brachydactyly. In individuals affected with geleophysic dysplasia, there is a significant increase in total active TGF-beta 1 and nuclear locations of p-SAMD2 in fibroblasts. Interestingly, ADAMTS-L2 interacts with LTBP-1, a glycoprotein that is part of the platelet-derived TGF-beta 1 complex.
中文(wén)名稱(chēng):FITC標(biāo)記(jì)的(dí)整(zhěng)合素樣(yàng)金(jīn)屬(shǔ)蛋(dàn)白酶(méi)與凝血酶樣(yàng)2蛋白(bái)抗體(tǐ)
別(bié) 名ADAMTS like 2; ADAMTS like protein 2; ADAMTS-like protein 2; ADAMTSL 2; ADAMTSL-2; ADAMTSL2; ATL2_HUMAN.
詳細介(jiè)紹(shào)：
規格:100ul
說(shuō) 明 書(shū)100ul
研究(jiū)領(lǐng)域腫瘤(liú) 心血管 細胞(bāo)生物 免疫(yì)學 信(xìn)號(hào)轉導 生(shēng)長(cháng)因子和激素(sù) 細胞(bāo)粘附(fù)分(fēn)子
抗體(tǐ)來源Rabbit
克隆(lóng)類型(xíng)Polyclonal
交叉反(fǎn)應 Human, Mouse, Rat,
產品應(yīng)用(yòng)IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子(zǐ) 量102kDa
性 狀Lyophilized or Liquid
濃(nóng) 度1mg/ml
免 疫 原(yuán)KLH conjugated synthetic peptide derived from human ADAMTSL2
亞(yà) 型IgG
純化方(fāng)法(fǎ)affinity purified by Protein A
儲 存(cún) 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條(tiáo)件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相關資料(liào)：
產(chǎn)品介紹background:
ADAMTS (A Disintegrin And Metalloproteinase Domain with Thrombospondin type 1 Modules) is a family of zinc-dependent proteases that are implicated in a variety of normal and pathological conditions, including arthritis and cancer. ADAMTS protein family members contain an amino-terminal propeptide domain, a metalloproteinase domain, a disintegrin-like domain and a carboxy-terminus that contains a varying number of Thrombospondin type 1 (TSP-1) motifs. ADAMTS-L2 (ADAMTS-like protein 2) is a 951 amino acid secreted protein that is highly expressed in lung, kidney and liver. Mutations in the gene encoding ADAMTS are the cause of geleophysic dysplasia, an autosomal recessive disorder characterized by cardiac vavular anomalies, short stature, thick skin and brachydactyly. In individuals affected with geleophysic dysplasia, there is a significant increase in total active TGF-beta 1 and nuclear locations of p-SAMD2 in fibroblasts. Interestingly, ADAMTS-L2 interacts with LTBP-1, a glycoprotein that is part of the platelet-derived TGF-beta 1 complex.
