首頁 > 產品中(zhōng)心 > 科研抗(kàng)體 > 標記一抗
產品中心(xīn)
標(biāo)記(jì)一抗
FITC標(biāo)記(jì)的整(zhěng)合素(sù)樣(yàng)金屬(shǔ)蛋(dàn)白酶與凝血酶(méi)9型(xíng)抗體(tǐ)
英(yīng)文(wén)名稱(chēng)Anti-ADAMTS9/FITC
中(zhōng)文名(míng)稱:FITC標記的整(zhěng)合素樣(yàng)金屬蛋(dàn)白(bái)酶(méi)與(yǔ)凝血酶(méi)9型抗體
別 名A disintegrin and metalloproteinase with thrombospondin motifs 9; ADAM TS 9; ADAM TS9; A disintegrin and metalloproteinase with thrombospondin motifs 9; A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 9; A disintegrin like and metalloprotease with thrombospondin type 1 motif 9; ADAM metallopeptidase with thrombospondin type 1 motif 9; ADAM TS 9; ADAM TS9; ADAMTS 9; ADAMTS9; ADAMTS-9; ATS9_HUMAN.
規格:100ul
說 明 書100ul
研究(jiū)領(lǐng)域腫(zhǒng)瘤(liú) 細胞生(shēng)物 免(miǎn)疫學 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞粘附分子(zǐ) 鋅指(zhǐ)蛋白
抗體來源(yuán)Rabbit
克隆類(lèi)型(xíng)Polyclonal
交叉反(fǎn)應 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
產品應(yīng)用(yòng)IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量181kDa
性 狀Lyophilized or Liquid
濃(nóng) 度1mg/ml
免 疫 原(yuán)KLH conjugated synthetic peptide derived from human ADAMTS9
亞 型(xíng)IgG
純化方法(fǎ)affinity purified by Protein A
儲 存 液(yè)0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存(cún)條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品(pǐn)介紹background:
ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. ADAMTS9 is closest in homology to ADAMTS20, sharing 54% overall identity, and like ADAMTS20 ADAMTS9 gas a GON like domain at the carboxyterminal end. The GON domain at the carboxyterminal end is similar to the GON1 protein in C. elegans, mutations of which lead to defective gonadal development. ADAMTS9 is expressed in ovary and testis, but little is known about the role of ADAMTS9 in reproductive organs. ADAMTS9 is also expressed in the heart, placenta, lung, skeletal tissue, and pancreas, so the protein must have wider functions than just gonadal development. ADAMTS9, like ADAMTS20, has a total of 15 thrombospondin like domains. The first TS domain begins shortly after the catalytic and disintegrin domains. TS domains 2 to 6 follow a spacer domain, followed by linker domain 1, then TS domains 7 & 8, linker domain 2, and then TS domains 9 to 15. In other ADAMTS proteins the TS motifs are thought to bind to the ECM. The ADAMTS proteins contain at least one prohormone convertase cleavage site, although it appears that one site is used preferentially, and cleavage of the propeptide domain at this site generates active enzymes. For ADAMTS9, this site is the RRTKR sequence, and the mature ADAMTS9 has an aminoterminal sequence of FLSYPR. The catalytic site of ADAMTS9 is most like ADAMTS1, 14 and 15, with an HExxHVFNMxH sequence, perhaps giving these enzymes some shared specificity.
中(zhōng)文名(míng)稱:FITC標記的整(zhěng)合素樣(yàng)金屬蛋(dàn)白(bái)酶(méi)與(yǔ)凝血酶(méi)9型抗體
別 名A disintegrin and metalloproteinase with thrombospondin motifs 9; ADAM TS 9; ADAM TS9; A disintegrin and metalloproteinase with thrombospondin motifs 9; A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 9; A disintegrin like and metalloprotease with thrombospondin type 1 motif 9; ADAM metallopeptidase with thrombospondin type 1 motif 9; ADAM TS 9; ADAM TS9; ADAMTS 9; ADAMTS9; ADAMTS-9; ATS9_HUMAN.
詳細介紹：
規格:100ul
說 明 書100ul
研究(jiū)領(lǐng)域腫(zhǒng)瘤(liú) 細胞生(shēng)物 免(miǎn)疫學 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞粘附分子(zǐ) 鋅指(zhǐ)蛋白
抗體來源(yuán)Rabbit
克隆類(lèi)型(xíng)Polyclonal
交叉反(fǎn)應 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
產品應(yīng)用(yòng)IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量181kDa
性 狀Lyophilized or Liquid
濃(nóng) 度1mg/ml
免 疫 原(yuán)KLH conjugated synthetic peptide derived from human ADAMTS9
亞 型(xíng)IgG
純化方法(fǎ)affinity purified by Protein A
儲 存 液(yè)0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存(cún)條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相關(guān)資(zī)料：
產(chǎn)品(pǐn)介紹background:
ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. ADAMTS9 is closest in homology to ADAMTS20, sharing 54% overall identity, and like ADAMTS20 ADAMTS9 gas a GON like domain at the carboxyterminal end. The GON domain at the carboxyterminal end is similar to the GON1 protein in C. elegans, mutations of which lead to defective gonadal development. ADAMTS9 is expressed in ovary and testis, but little is known about the role of ADAMTS9 in reproductive organs. ADAMTS9 is also expressed in the heart, placenta, lung, skeletal tissue, and pancreas, so the protein must have wider functions than just gonadal development. ADAMTS9, like ADAMTS20, has a total of 15 thrombospondin like domains. The first TS domain begins shortly after the catalytic and disintegrin domains. TS domains 2 to 6 follow a spacer domain, followed by linker domain 1, then TS domains 7 & 8, linker domain 2, and then TS domains 9 to 15. In other ADAMTS proteins the TS motifs are thought to bind to the ECM. The ADAMTS proteins contain at least one prohormone convertase cleavage site, although it appears that one site is used preferentially, and cleavage of the propeptide domain at this site generates active enzymes. For ADAMTS9, this site is the RRTKR sequence, and the mature ADAMTS9 has an aminoterminal sequence of FLSYPR. The catalytic site of ADAMTS9 is most like ADAMTS1, 14 and 15, with an HExxHVFNMxH sequence, perhaps giving these enzymes some shared specificity.
