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英(yīng)文名稱(chēng)Anti-phospho-AKT3 (Ser472)/FITC
中文名稱:FITC標(biāo)記的磷(lín)酸化蛋白激(jī)酶AKT3抗體(tǐ)
別 名(míng)Akt3; AKT3 kinase; AKT3_HUMAN; DKFZp434N0250; PKB gamma; PKBG; PRKBG; Protein kinase Akt-3; Protein Kinase AKT3; Protein kinase B gamma; RAC gamma; RAC gamma serine/threonine protein kinase; RAC-gamma serine/threonine-protein kinase; RAC-PK-gamma; RACPK Gamma; Serine threonine protein kinase Akt 3; Serine threonine protein kinase Akt3; STK 2; STK-2; STK2; V akt murine thymoma viral oncogene homolog 3 protein kinase B gamma.
規格:100ul
說(shuō) 明(míng) 書(shū)100ul
產品類型(xíng)磷酸化抗體
研(yán)究領(lǐng)域(yù)腫(zhǒng)瘤 細胞生(shēng)物 免(miǎn)疫學 信(xìn)號(hào)轉導(dǎo) 激(jī)酶和(hé)磷酸酶(méi)
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反(fǎn)應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,
產品(pǐn)應用(yòng)IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子(zǐ) 量(liáng)56kDa
細(xì)胞(bāo)定位(wèi)細(xì)胞膜(mó)
性(xìng) 狀(zhuàng)Lyophilized or Liquid
濃 度(dù)1mg/ml
免 疫(yì) 原KLH conjugated Synthesised phosphopeptide derived from human AKT3 around the phosphorylation site of Ser472
亞 型IgG
純化方法(fǎ)affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存(cún)條件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介(jiè)紹(shào)background:
Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphtidylinositol 3 kinase (PI 3 kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer as the tumor suppressor PTEN was found to antagonise PI3 kinase and Akt/PKB kinase activity. There are 3 known isoforms of this enzyme in mammalian cells (1/alpha, 2/beta and 3/gamma). IGF1 leads to the activation of AKT3, which may play a role in regulating cell survival. It is capable of phosphorylating several known proteins.
中文名稱:FITC標(biāo)記的磷(lín)酸化蛋白激(jī)酶AKT3抗體(tǐ)
別 名(míng)Akt3; AKT3 kinase; AKT3_HUMAN; DKFZp434N0250; PKB gamma; PKBG; PRKBG; Protein kinase Akt-3; Protein Kinase AKT3; Protein kinase B gamma; RAC gamma; RAC gamma serine/threonine protein kinase; RAC-gamma serine/threonine-protein kinase; RAC-PK-gamma; RACPK Gamma; Serine threonine protein kinase Akt 3; Serine threonine protein kinase Akt3; STK 2; STK-2; STK2; V akt murine thymoma viral oncogene homolog 3 protein kinase B gamma.
詳(xiáng)細(xì)介(jiè)紹：
規格:100ul
說(shuō) 明(míng) 書(shū)100ul
產品類型(xíng)磷酸化抗體
研(yán)究領(lǐng)域(yù)腫(zhǒng)瘤 細胞生(shēng)物 免(miǎn)疫學 信(xìn)號(hào)轉導(dǎo) 激(jī)酶和(hé)磷酸酶(méi)
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反(fǎn)應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,
產品(pǐn)應用(yòng)IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子(zǐ) 量(liáng)56kDa
細(xì)胞(bāo)定位(wèi)細(xì)胞膜(mó)
性(xìng) 狀(zhuàng)Lyophilized or Liquid
濃 度(dù)1mg/ml
免 疫(yì) 原KLH conjugated Synthesised phosphopeptide derived from human AKT3 around the phosphorylation site of Ser472
亞 型IgG
純化方法(fǎ)affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存(cún)條件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相關資料：
產品介(jiè)紹(shào)background:
Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphtidylinositol 3 kinase (PI 3 kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer as the tumor suppressor PTEN was found to antagonise PI3 kinase and Akt/PKB kinase activity. There are 3 known isoforms of this enzyme in mammalian cells (1/alpha, 2/beta and 3/gamma). IGF1 leads to the activation of AKT3, which may play a role in regulating cell survival. It is capable of phosphorylating several known proteins.
- 上(shàng)一條(tiáo)：FITC標記的(dí)磷酸化(huà)自(zì)噬相關蛋(dàn)白4A抗體
- 下(xià)一(yī)條(tiáo)：FITC標(biāo)記的(dí)磷(lín)酸化腫(zhǒng)瘤血管內(nèi)皮標(biāo)誌物(wù)8抗體(tǐ)
