產品中心(xīn)
標記(jì)一抗
英文(wén)名(míng)稱(chēng)Anti-AKT3/FITC
中文名(míng)稱(chēng):FITC標(biāo)記的蛋白激酶(méi)B3
別 名AKT3 kinase; DKFZP434N0250; PKB Gamma; PKBG; PRKBG; Protein Kinase AKT3; Protein Kinase B Gamma; RAC gamma; RAC Gamma Serine/Threonine Protein Kinase; RACPK Gamma; Serine threonine protein kinase Akt 3; Serine Threonine Protein Kinase AKT3; STK 2; STK2; V akt murine thymoma viral oncogene homolog 3 protein kinase B gamma; VAKT Murine Thymoma Viral Oncogene Homolog 3; AKT3_HUMAN.
規格(gé):100ul
說 明(míng) 書(shū)100ul
研(yán)究(jiū)領(lǐng)域腫瘤 細胞生物 免疫(yì)學(xué) 信號轉(zhuǎn)導 轉錄調(tiáo)節因子 激酶和磷酸酶
抗體來(lái)源Rabbit
克(kè)隆(lóng)類(lèi)型(xíng)Polyclonal
交(jiāo)叉反應 Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit, Sheep,
產品(pǐn)應用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分(fēn) 子 量56kDa
細胞定(dìng)位細胞膜
性 狀Lyophilized or Liquid
濃 度1mg/ml
免(miǎn) 疫 原(yuán)KLH conjugated synthetic peptide derived from human AKT3
亞(yà) 型(xíng)IgG
純(chún)化(huà)方法affinity purified by Protein A
儲 存(cún) 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存條件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介(jiè)紹background:
Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphtidylinositol 3 kinase (PI 3 kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer as the tumor suppressor PTEN was found to antagonise PI3 kinase and Akt/PKB kinase activity. There are 3 known isoforms of this enzyme in mammalian cells (1/alpha, 2/beta and 3/gamma). IGF1 leads to the activation of AKT3, which may play a role in regulating cell survival. It is capable of phosphorylating several known proteins.
中文名(míng)稱(chēng):FITC標(biāo)記的蛋白激酶(méi)B3
別 名AKT3 kinase; DKFZP434N0250; PKB Gamma; PKBG; PRKBG; Protein Kinase AKT3; Protein Kinase B Gamma; RAC gamma; RAC Gamma Serine/Threonine Protein Kinase; RACPK Gamma; Serine threonine protein kinase Akt 3; Serine Threonine Protein Kinase AKT3; STK 2; STK2; V akt murine thymoma viral oncogene homolog 3 protein kinase B gamma; VAKT Murine Thymoma Viral Oncogene Homolog 3; AKT3_HUMAN.
詳(xiáng)細(xì)介紹：
規格(gé):100ul
說 明(míng) 書(shū)100ul
研(yán)究(jiū)領(lǐng)域腫瘤 細胞生物 免疫(yì)學(xué) 信號轉(zhuǎn)導 轉錄調(tiáo)節因子 激酶和磷酸酶
抗體來(lái)源Rabbit
克(kè)隆(lóng)類(lèi)型(xíng)Polyclonal
交(jiāo)叉反應 Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit, Sheep,
產品(pǐn)應用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分(fēn) 子 量56kDa
細胞定(dìng)位細胞膜
性 狀Lyophilized or Liquid
濃 度1mg/ml
免(miǎn) 疫 原(yuán)KLH conjugated synthetic peptide derived from human AKT3
亞(yà) 型(xíng)IgG
純(chún)化(huà)方法affinity purified by Protein A
儲 存(cún) 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保(bǎo)存條件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相關(guān)資料(liào)：
產(chǎn)品介(jiè)紹background:
Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphtidylinositol 3 kinase (PI 3 kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer as the tumor suppressor PTEN was found to antagonise PI3 kinase and Akt/PKB kinase activity. There are 3 known isoforms of this enzyme in mammalian cells (1/alpha, 2/beta and 3/gamma). IGF1 leads to the activation of AKT3, which may play a role in regulating cell survival. It is capable of phosphorylating several known proteins.
