產(chǎn)品中(zhōng)心(xīn)
標記一抗(kàng)
英(yīng)文名稱Anti-AMBRA1/FITC
中文名稱:FITC標(biāo)記的自噬(shì)相關(guān)基因(yīn)AMBRA1抗(kàng)體(tǐ)
別 名(míng)Activating molecule in beclin 1 regulated autophagy; Activating molecule in BECN1 regulated autophagy protein 1; Hypothetical protein FLJ20294; Hypothetical protein LOC55626; KIAA1736; MGC33725; WDR94; AMRA1_HUMAN.
規(guī)格:100ul
說 明(míng) 書(shū)100ul
研(yán)究(jiū)領域腫(zhǒng)瘤 心(xīn)血(xiě)管(guǎn) 細(xì)胞生(shēng)物 免疫學 發(fā)育生物(wù)學 神經生物學(xué) 細菌(jūn)及病毒(dú)
抗體來源Rabbit
克隆(lóng)類型(xíng)Polyclonal
交叉(chā)反應 Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit,
產品(pǐn)應用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量143kDa
性 狀Lyophilized or Liquid
濃(nóng) 度1mg/ml
免(miǎn) 疫(yì) 原KLH conjugated synthetic peptide derived from human AMBRA1 N-terminus
亞 型(xíng)IgG
純(chún)化(huà)方法affinity purified by Protein A
儲 存(cún) 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存(cún)條件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹background:
AMBRA1 regulates autophagy and development of the nervous system. It is a large, previously unknown protein bearing a WD40 domain at its amino terminus, regulates autophagy and has a crucial role in embryogenesis. AMBRA1 is a positive regulator of the Becn1-dependent programme of autophagy, as revealed by its overexpression and by RNA interference experiments invitro. Notably, AMBRA1 functional deficiency in mouse embryos leads to severe neural tube defects associated with autophagy impairment, accumulation of ubiquitinated proteins, unbalanced cell proliferation and excessive apoptotic cell death.
中文名稱:FITC標(biāo)記的自噬(shì)相關(guān)基因(yīn)AMBRA1抗(kàng)體(tǐ)
別 名(míng)Activating molecule in beclin 1 regulated autophagy; Activating molecule in BECN1 regulated autophagy protein 1; Hypothetical protein FLJ20294; Hypothetical protein LOC55626; KIAA1736; MGC33725; WDR94; AMRA1_HUMAN.
詳細介紹：
規(guī)格:100ul
說 明(míng) 書(shū)100ul
研(yán)究(jiū)領域腫(zhǒng)瘤 心(xīn)血(xiě)管(guǎn) 細(xì)胞生(shēng)物 免疫學 發(fā)育生物(wù)學 神經生物學(xué) 細菌(jūn)及病毒(dú)
抗體來源Rabbit
克隆(lóng)類型(xíng)Polyclonal
交叉(chā)反應 Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit,
產品(pǐn)應用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量143kDa
性 狀Lyophilized or Liquid
濃(nóng) 度1mg/ml
免(miǎn) 疫(yì) 原KLH conjugated synthetic peptide derived from human AMBRA1 N-terminus
亞 型(xíng)IgG
純(chún)化(huà)方法affinity purified by Protein A
儲 存(cún) 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存(cún)條件(jiàn)Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相關(guān)資料(liào)：
產品介紹background:
AMBRA1 regulates autophagy and development of the nervous system. It is a large, previously unknown protein bearing a WD40 domain at its amino terminus, regulates autophagy and has a crucial role in embryogenesis. AMBRA1 is a positive regulator of the Becn1-dependent programme of autophagy, as revealed by its overexpression and by RNA interference experiments invitro. Notably, AMBRA1 functional deficiency in mouse embryos leads to severe neural tube defects associated with autophagy impairment, accumulation of ubiquitinated proteins, unbalanced cell proliferation and excessive apoptotic cell death.
