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英(yīng)文(wén)名(míng)稱 Anti-ADH6
中文(wén)名(míng)稱 乙(yǐ)醇脫(tuō)氫(qīng)酶6抗(kàng)體(tǐ)
別 名 ADH 5; ADH 6; Adh6; ADH6_HUMAN; Alcohol dehydrogenase 6 (class V); Alcohol dehydrogenase 6; Aldehyde reductase; Class V alcohol dehydrogenase 6; UDP GLUCURONOSYLTRANSFERASE 2B10 PRECURSOR, MICROSOMAL.
濃 度 1mg/1ml
規(guī) 格(gé) 0.2ml/200μg
抗(kàng)體來(lái)源 Rabbit
克隆類(lèi)型(xíng) polyclonal
交叉反應 Human, Mouse, Rat, Pig, Cow
產品類(lèi)型 一抗
研(yán)究領域 腫瘤(liú) 細(xì)胞生(shēng)物 信號轉(zhuǎn)導 新(xīn)陳代謝(xiè)
蛋白(bái)分子(zǐ)量(liáng) predicted molecular weight: 39kDa
性 狀 Lyophilized or Liquid
免 疫(yì) 原(yuán) KLH conjugated synthetic peptide derived from human ADH6
亞 型 IgG
純化(huà)方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應用(yòng) WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蠟切片(piàn)需做(zuò)抗原(yuán)修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保(bǎo)存條件(jiàn) Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介(jiè)紹 ADH6 (alcohol dehydrogenase 6), also known as ADH-5, is a 368 amino acid member of the class V zinc-containing alcohol dehydrogenase family. This family of enzymes functions to metabolize a wide variety of substrates such as retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. Localized to the cytoplasm and expressed in the stomach and liver, ADH6 catalyzes the reversible oxidation of alcohols to their corresponding aldehydes or ketones and is able to bind two zinc ions as cofactors. ADH6 contains a glucocorticoid response element upstream of its 5' UTR which is thought to be a steroid binding site, suggesting that expression of ADH6 may be under hormonal control. Multiple isoforms of ADH6 exist due to alternative splicing events.
Subcellular Location : Cytoplasm.
Tissue Specificity : Stomach and liver.
Similarity : Belongs to the zinc-containing alcohol dehydrogenase family. Class-V subfamily.
Database links : UniProtKB/Swiss-Prot: P28332.2
產品介(jiè)紹(shào) ADH6 (alcohol dehydrogenase 6), also known as ADH-5, is a 368 amino acid member of the class V zinc-containing alcohol dehydrogenase family. This family of enzymes functions to metabolize a wide variety of substrates such as retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. Localized to the cytoplasm and expressed in the stomach and liver, ADH6 catalyzes the reversible oxidation of alcohols to their corresponding aldehydes or ketones and is able to bind two zinc ions as cofactors. ADH6 contains a glucocorticoid response element upstream of its 5' UTR which is thought to be a steroid binding site, suggesting that expression of ADH6 may be under hormonal control. Multiple isoforms of ADH6 exist due to alternative splicing events.
Subcellular Location : Cytoplasm.
Tissue Specificity : Stomach and liver.
Similarity : Belongs to the zinc-containing alcohol dehydrogenase family. Class-V subfamily.
Database links : UniProtKB/Swiss-Prot: P28332.2
中文(wén)名(míng)稱 乙(yǐ)醇脫(tuō)氫(qīng)酶6抗(kàng)體(tǐ)
別 名 ADH 5; ADH 6; Adh6; ADH6_HUMAN; Alcohol dehydrogenase 6 (class V); Alcohol dehydrogenase 6; Aldehyde reductase; Class V alcohol dehydrogenase 6; UDP GLUCURONOSYLTRANSFERASE 2B10 PRECURSOR, MICROSOMAL.
詳細介紹:
濃 度 1mg/1ml
規(guī) 格(gé) 0.2ml/200μg
抗(kàng)體來(lái)源 Rabbit
克隆類(lèi)型(xíng) polyclonal
交叉反應 Human, Mouse, Rat, Pig, Cow
產品類(lèi)型 一抗
研(yán)究領域 腫瘤(liú) 細(xì)胞生(shēng)物 信號轉(zhuǎn)導 新(xīn)陳代謝(xiè)
蛋白(bái)分子(zǐ)量(liáng) predicted molecular weight: 39kDa
性 狀 Lyophilized or Liquid
免 疫(yì) 原(yuán) KLH conjugated synthetic peptide derived from human ADH6
亞 型 IgG
純化(huà)方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應用(yòng) WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蠟切片(piàn)需做(zuò)抗原(yuán)修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保(bǎo)存條件(jiàn) Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介(jiè)紹 ADH6 (alcohol dehydrogenase 6), also known as ADH-5, is a 368 amino acid member of the class V zinc-containing alcohol dehydrogenase family. This family of enzymes functions to metabolize a wide variety of substrates such as retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. Localized to the cytoplasm and expressed in the stomach and liver, ADH6 catalyzes the reversible oxidation of alcohols to their corresponding aldehydes or ketones and is able to bind two zinc ions as cofactors. ADH6 contains a glucocorticoid response element upstream of its 5' UTR which is thought to be a steroid binding site, suggesting that expression of ADH6 may be under hormonal control. Multiple isoforms of ADH6 exist due to alternative splicing events.
Subcellular Location : Cytoplasm.
Tissue Specificity : Stomach and liver.
Similarity : Belongs to the zinc-containing alcohol dehydrogenase family. Class-V subfamily.
Database links : UniProtKB/Swiss-Prot: P28332.2
相關(guān)資料(liào):
產品介(jiè)紹(shào) ADH6 (alcohol dehydrogenase 6), also known as ADH-5, is a 368 amino acid member of the class V zinc-containing alcohol dehydrogenase family. This family of enzymes functions to metabolize a wide variety of substrates such as retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. Localized to the cytoplasm and expressed in the stomach and liver, ADH6 catalyzes the reversible oxidation of alcohols to their corresponding aldehydes or ketones and is able to bind two zinc ions as cofactors. ADH6 contains a glucocorticoid response element upstream of its 5' UTR which is thought to be a steroid binding site, suggesting that expression of ADH6 may be under hormonal control. Multiple isoforms of ADH6 exist due to alternative splicing events.
Subcellular Location : Cytoplasm.
Tissue Specificity : Stomach and liver.
Similarity : Belongs to the zinc-containing alcohol dehydrogenase family. Class-V subfamily.
Database links : UniProtKB/Swiss-Prot: P28332.2
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