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一(yī)抗
英(yīng)文名稱 Anti-Argonaute 3/eIF2C3
中(zhōng)文名(míng)稱 真(zhēn)核翻(fān)譯起始因(yīn)子2C3抗體
別 名(míng) Argonaute 3/eIF2C 3; 5730550L01Rik; Ago 3; Ago3; AGO3_HUMAN; argonaute 3; Argonaute3; eIF 2C 3; eIF-2C 3; eIF2C 3; Eif2c3; eIF2C3; EIF2C3 protein; Eukaryotic translation initiation factor 2C 3; Eukaryotic translation initiation factor 2C3; FLJ12765; hAgo3; MGC86946; Protein argonaute-3.
濃(nóng) 度(dù) 1mg/1ml
規(guī) 格(gé) 0.2ml/200μg
抗體來(lái)源(yuán) Rabbit
克隆(lóng)類型 polyclonal
交叉(chā)反(fǎn)應 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
產品類型(xíng) 一(yī)抗(kàng)
研(yán)究領域 細(xì)胞(bāo)生(shēng)物 表觀遺傳學
蛋白(bái)分子量(liáng) predicted molecular weight: 97kDa
性(xìng) 狀(zhuàng) Lyophilized or Liquid
免(miǎn) 疫(yì) 原 KLH conjugated synthetic peptide derived from human Argonaute 3/eIF2C3
亞 型 IgG
純化(huà)方法 affinity purified by Protein A
儲(chǔ) 存 液(yè) Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產品(pǐn)應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟(là)切片需(xū)做抗(kàng)原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介(jiè)紹(shào) Eukaryotic translation initiation factor 2C (eIF2C) proteins (argonaute family) influence RNA interference (RNAi) as components of the RNA-inducible silencing complex (RISC) or microRNA (miRNA)-containing ribonucleoprotein particle (miRNP). Small RNAs, including small interfering RNAs (siRNAs) and miRNAs, can silence target genes through mechanisms that utilize RISC or miRNP particles. eIF2C1 (argonaute 1, AGO1, eIF2C, GERP95, Q99) and Dicer1 play a coordinated role in siRNA-mediated gene silencing. eIF2C2 (Slicer, argonaute 2, AGO2, Q10) is a RISC component that can concentrate in cytoplasmic processing bodies (P-bodies) and catalyze mRNA cleavage. Mammalian P-bodies contain mRNAs and have an association with miRNA-induced translational silencing and siRNA-induced mRNA degradation. Additional eIF2C proteins include eIF2C3 (argonaute 3, AGO3), eIF2C4 (argonaute 4, AGO4) and meIF2c5 (mouse argonaute 5).
Function : Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.
Subunit : Interacts with EIF4B, IMP8, PRMT5 and TNRC6B. Interacts with APOBEC3F, APOBEC3G and APOBEC3H.
Subcellular Location : Cytoplasm.
Similarity : Belongs to the argonaute family. Ago subfamily.
Contains 1 PAZ domain.
Contains 1 Piwi domain.
Database links : UniProtKB/Swiss-Prot: Q9H9G7.2
中(zhōng)文名(míng)稱 真(zhēn)核翻(fān)譯起始因(yīn)子2C3抗體
別 名(míng) Argonaute 3/eIF2C 3; 5730550L01Rik; Ago 3; Ago3; AGO3_HUMAN; argonaute 3; Argonaute3; eIF 2C 3; eIF-2C 3; eIF2C 3; Eif2c3; eIF2C3; EIF2C3 protein; Eukaryotic translation initiation factor 2C 3; Eukaryotic translation initiation factor 2C3; FLJ12765; hAgo3; MGC86946; Protein argonaute-3.
詳細介紹：
濃(nóng) 度(dù) 1mg/1ml
規(guī) 格(gé) 0.2ml/200μg
抗體來(lái)源(yuán) Rabbit
克隆(lóng)類型 polyclonal
交叉(chā)反(fǎn)應 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
產品類型(xíng) 一(yī)抗(kàng)
研(yán)究領域 細(xì)胞(bāo)生(shēng)物 表觀遺傳學
蛋白(bái)分子量(liáng) predicted molecular weight: 97kDa
性(xìng) 狀(zhuàng) Lyophilized or Liquid
免(miǎn) 疫(yì) 原 KLH conjugated synthetic peptide derived from human Argonaute 3/eIF2C3
亞 型 IgG
純化(huà)方法 affinity purified by Protein A
儲(chǔ) 存 液(yè) Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產品(pǐn)應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟(là)切片需(xū)做抗(kàng)原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相關資(zī)料(liào)：
產品介(jiè)紹(shào) Eukaryotic translation initiation factor 2C (eIF2C) proteins (argonaute family) influence RNA interference (RNAi) as components of the RNA-inducible silencing complex (RISC) or microRNA (miRNA)-containing ribonucleoprotein particle (miRNP). Small RNAs, including small interfering RNAs (siRNAs) and miRNAs, can silence target genes through mechanisms that utilize RISC or miRNP particles. eIF2C1 (argonaute 1, AGO1, eIF2C, GERP95, Q99) and Dicer1 play a coordinated role in siRNA-mediated gene silencing. eIF2C2 (Slicer, argonaute 2, AGO2, Q10) is a RISC component that can concentrate in cytoplasmic processing bodies (P-bodies) and catalyze mRNA cleavage. Mammalian P-bodies contain mRNAs and have an association with miRNA-induced translational silencing and siRNA-induced mRNA degradation. Additional eIF2C proteins include eIF2C3 (argonaute 3, AGO3), eIF2C4 (argonaute 4, AGO4) and meIF2c5 (mouse argonaute 5).
Function : Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.
Subunit : Interacts with EIF4B, IMP8, PRMT5 and TNRC6B. Interacts with APOBEC3F, APOBEC3G and APOBEC3H.
Subcellular Location : Cytoplasm.
Similarity : Belongs to the argonaute family. Ago subfamily.
Contains 1 PAZ domain.
Contains 1 Piwi domain.
Database links : UniProtKB/Swiss-Prot: Q9H9G7.2
- 上(shàng)一條：真(zhēn)核(hé)翻譯起(qǐ)始因(yīn)子2C4抗體(tǐ)
- 下(xià)一條：精(jīng)氨(ān)酰tRNA合成(chéng)酶抗體(tǐ)
