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磷(lín)酸(suān)化(huà)乳(rǔ)腺(xiàn)癌易感(gǎn)基因相(xiāng)互作(zuò)用蛋白1抗體
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2017-5-4 瀏(liú)覽次數(shù)：1822
英文(wén)名(míng)稱 Anti-phospho-BACH1/BRIP1(Ser990)
中(zhōng)文名稱： 磷酸(suān)化乳(rǔ)腺癌(ái)易感基(jī)因(yīn)相(xiāng)互作用蛋(dàn)白1抗(kàng)體(tǐ)
別(bié) 名 BACH 1; BRIP1; BACH-1; BRAC 1 Associated C Terminal Helicase 1; BRCA 1 Interacting Protein 1; BRCA1 binding helicase like protein BACH1; BRCA1 interacting protein C terminal helicase 1; BRIP 1; BRIP-1; FANCJ; ATP dependent RNA helicase BRIP1; Fanconi anemia group J protein; FLJ90232; MGC126521; MGC126523; OF antibody Protein FACJ; FANCJ_HUMAN.
濃(nóng) 度 1mg/1ml
規 格 0.1ml/100μg
抗(kàng)體(tǐ)來(lái)源 Rabbit
克隆類型 polyclonal
交叉反應(yīng) Human, Cow, Sheep
產品類型(xíng) 一抗(kàng) 磷(lín)酸化抗體
研(yán)究(jiū)領域(yù) 腫(zhǒng)瘤 免疫學(xué) 信號(hào)轉導(dǎo)
蛋(dàn)白(bái)分(fēn)子量(liáng) predicted molecular weight: 141kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human BRIP1 around the phosphorylation site of Ser990
亞(yà) 型(xíng) IgG
純化(huà)方(fāng)法(fǎ) affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產(chǎn)品(pǐn)應用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保(bǎo)存條件(jiàn) Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹(shào) BACH1 is a member of the DEAH helicase family that interacts with BRCA1, in vivo. BACH1 is a DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. BACH1 acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination, and is involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1. The BACH1/BRCA1 complex formation contributes to a key function of BRCA1. Therefore, it is likely that BACH1 is a target of germline cancer-inducing mutations.
Function : Transcriptional regulator that acts as repressor or activator. Binds, in-vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.
Subcellular Location : Nucleus.
Similarity : Belongs to the bZIP family. CNC subfamily.
Contains 1 BTB (POZ) domain.
Contains 1 bZIP domain.
Database links : UniProtKB/Swiss-Prot: Q9BX63.1
中(zhōng)文名稱： 磷酸(suān)化乳(rǔ)腺癌(ái)易感基(jī)因(yīn)相(xiāng)互作用蛋(dàn)白1抗(kàng)體(tǐ)
別(bié) 名 BACH 1; BRIP1; BACH-1; BRAC 1 Associated C Terminal Helicase 1; BRCA 1 Interacting Protein 1; BRCA1 binding helicase like protein BACH1; BRCA1 interacting protein C terminal helicase 1; BRIP 1; BRIP-1; FANCJ; ATP dependent RNA helicase BRIP1; Fanconi anemia group J protein; FLJ90232; MGC126521; MGC126523; OF antibody Protein FACJ; FANCJ_HUMAN.
詳細(xì)介(jiè)紹(shào)：
濃(nóng) 度 1mg/1ml
規 格 0.1ml/100μg
抗(kàng)體(tǐ)來(lái)源 Rabbit
克隆類型 polyclonal
交叉反應(yīng) Human, Cow, Sheep
產品類型(xíng) 一抗(kàng) 磷(lín)酸化抗體
研(yán)究(jiū)領域(yù) 腫(zhǒng)瘤 免疫學(xué) 信號(hào)轉導(dǎo)
蛋(dàn)白(bái)分(fēn)子量(liáng) predicted molecular weight: 141kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human BRIP1 around the phosphorylation site of Ser990
亞(yà) 型(xíng) IgG
純化(huà)方(fāng)法(fǎ) affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產(chǎn)品(pǐn)應用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保(bǎo)存條件(jiàn) Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相關(guān)資(zī)料(liào)：
產品介紹(shào) BACH1 is a member of the DEAH helicase family that interacts with BRCA1, in vivo. BACH1 is a DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. BACH1 acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination, and is involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1. The BACH1/BRCA1 complex formation contributes to a key function of BRCA1. Therefore, it is likely that BACH1 is a target of germline cancer-inducing mutations.
Function : Transcriptional regulator that acts as repressor or activator. Binds, in-vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.
Subcellular Location : Nucleus.
Similarity : Belongs to the bZIP family. CNC subfamily.
Contains 1 BTB (POZ) domain.
Contains 1 bZIP domain.
Database links : UniProtKB/Swiss-Prot: Q9BX63.1
- 上一(yī)條：雙向染色(sè)體細胞分(fēn)裂蛋白1抗體
- 下(xià)一(yī)條：乳腺癌(ái)易(yì)感(gǎn)基因(yīn)相(xiāng)互作用蛋白1抗體(tǐ)
