產(chǎn)品(pǐn)中心
一抗(kàng)
英文(wén)名稱(chēng) Anti-BCMA/CD269
中(zhōng)文(wén)名稱： B淋巴細胞成(chéng)熟因(yīn)子(zǐ)抗體
別 名 B cell maturation antigen; B Cell Maturation Factor; B cell maturation protein; BCM; BCMA; CD269; CD269 antigen; TNFRSF17; Tumor Necrosis Factor Receptor Member 17; Tumor necrosis factor receptor superfamily member 17; TNR17_HUMAN.
濃(nóng) 度 1mg/1ml
規 格 0.1ml/100μg 0.2ml/200μg
抗體(tǐ)來(lái)源(yuán) Rabbit
克(kè)隆類型(xíng) polyclonal
交叉反應 Human, Mouse, Rat
產品類(lèi)型 一抗(kàng)
研(yán)究(jiū)領(lǐng)域 腫瘤(liú) 細胞(bāo)生物 免(miǎn)疫學 轉錄調(tiáo)節因子(zǐ) b-淋巴細(xì)胞(bāo)
蛋(dàn)白(bái)分子(zǐ)量 predicted molecular weight: 20kDa
性(xìng) 狀 Lyophilized or Liquid
免 疫(yì) 原 KLH conjugated synthetic peptide derived from human BCMA C-terminus
亞 型 IgG
純化方(fāng)法 affinity purified by Protein A
儲 存 液(yè) 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產(chǎn)品(pǐn)應用(yòng) WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 IF=1:100-500
（石蠟切片需做抗(kàng)原(yuán)修(xiū)復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條(tiáo)件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介(jiè)紹 The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq].
Function : Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Subunit : Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6.
Subcellular Location : Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein.
Tissue Specificity : Expressed in mature B-cells, but not in T-cells or monocytes.
DISEASE : Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
Similarity : Contains 1 TNFR-Cys repeat.
Database links : UniProtKB/Swiss-Prot: Q02223.2
中(zhōng)文(wén)名稱： B淋巴細胞成(chéng)熟因(yīn)子(zǐ)抗體
別 名 B cell maturation antigen; B Cell Maturation Factor; B cell maturation protein; BCM; BCMA; CD269; CD269 antigen; TNFRSF17; Tumor Necrosis Factor Receptor Member 17; Tumor necrosis factor receptor superfamily member 17; TNR17_HUMAN.
詳細介紹：
濃(nóng) 度 1mg/1ml
規 格 0.1ml/100μg 0.2ml/200μg
抗體(tǐ)來(lái)源(yuán) Rabbit
克(kè)隆類型(xíng) polyclonal
交叉反應 Human, Mouse, Rat
產品類(lèi)型 一抗(kàng)
研(yán)究(jiū)領(lǐng)域 腫瘤(liú) 細胞(bāo)生物 免(miǎn)疫學 轉錄調(tiáo)節因子(zǐ) b-淋巴細(xì)胞(bāo)
蛋(dàn)白(bái)分子(zǐ)量 predicted molecular weight: 20kDa
性(xìng) 狀 Lyophilized or Liquid
免 疫(yì) 原 KLH conjugated synthetic peptide derived from human BCMA C-terminus
亞 型 IgG
純化方(fāng)法 affinity purified by Protein A
儲 存 液(yè) 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產(chǎn)品(pǐn)應用(yòng) WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 IF=1:100-500
（石蠟切片需做抗(kàng)原(yuán)修(xiū)復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條(tiáo)件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相關資(zī)料：
產(chǎn)品介(jiè)紹 The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq].
Function : Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Subunit : Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6.
Subcellular Location : Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein.
Tissue Specificity : Expressed in mature B-cells, but not in T-cells or monocytes.
DISEASE : Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
Similarity : Contains 1 TNFR-Cys repeat.
Database links : UniProtKB/Swiss-Prot: Q02223.2
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