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英(yīng)文名稱 Anti-BRCAA1/RBBP1L1
中(zhōng)文(wén)名(míng)稱(chēng)： 乳腺癌(ái)相(xiāng)關(guān)抗(kàng)原BRCAA1抗體
別 名(míng) ARID 4B; ARID domain-containing protein 4B; ARID4B; AT rich interactive domain 4B (Rbp1 like); AT rich interactive domain 4B; BCAA; BRCAA 1; BRCAA1; Breast cancer associated antigen 1; Breast cancer associated antigen BRCAA 1; Breast cancer associated antigen BRCAA1; Breast carcinoma associated antigen; Histone deacetylase complex subunit SAP180; Rb binding protein homolog; RBBP1 L1; RBBP1L1; Rbp 1 like; Rbp1 l1; Rbp1 like; RBP1 like protein; RBP1L; Rbp1l1; Retinoblastoma binding protein 1 like 1; SAP 180; SAP180; SIN3A associated protein 180; ARI4B_HUMAN.
濃 度 1mg/1ml
規(guī) 格(gé) 0.2ml/200μg
抗體來源(yuán) Rabbit
克(kè)隆類(lèi)型 polyclonal
交(jiāo)叉反應 Human, Mouse, Rat, Chicken, Dog, Cow, Horse
產品(pǐn)類(lèi)型(xíng) 一抗
研(yán)究領域(yù) 腫(zhǒng)瘤 細胞生(shēng)物 免疫(yì)學 染(rǎn)色(sè)質和(hé)核信(xìn)號(hào) 細胞(bāo)類型標誌(zhì)物(wù)
性(xìng) 狀 Lyophilized or Liquid
免(miǎn) 疫(yì) 原 KLH conjugated synthetic peptide derived from human BRCAA1
亞(yà) 型 IgG
純(chún)化方(fāng)法 affinity purified by Protein A
儲(chǔ) 存(cún) 液(yè) 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產品應(yīng)用(yòng) ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蠟(là)切(qiē)片(piàn)需做(zuò)抗原(yuán)修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條(tiáo)件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹(shào) This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008].
Function : Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
Subunit : Component of a Sin3A corepressor complex consisting of SIN3A, SAP130, SUDS3/SAP45, SAP180, HDAC1 and HDAC2.
Subcellular Location : Nucleus (By similarity). Cytoplasm. Note=Cytoplasmic in breast cancer cells.
Tissue Specificity : Highly expressed in the testis and in breast, lung, colon, pancreatic and ovarian cancers. Expressed at low levels in the thymus, prostate and ovary.
Similarity : Contains 1 ARID domain.
Database links : UniProtKB/Swiss-Prot: Q4LE39.2
中(zhōng)文(wén)名(míng)稱(chēng)： 乳腺癌(ái)相(xiāng)關(guān)抗(kàng)原BRCAA1抗體
別 名(míng) ARID 4B; ARID domain-containing protein 4B; ARID4B; AT rich interactive domain 4B (Rbp1 like); AT rich interactive domain 4B; BCAA; BRCAA 1; BRCAA1; Breast cancer associated antigen 1; Breast cancer associated antigen BRCAA 1; Breast cancer associated antigen BRCAA1; Breast carcinoma associated antigen; Histone deacetylase complex subunit SAP180; Rb binding protein homolog; RBBP1 L1; RBBP1L1; Rbp 1 like; Rbp1 l1; Rbp1 like; RBP1 like protein; RBP1L; Rbp1l1; Retinoblastoma binding protein 1 like 1; SAP 180; SAP180; SIN3A associated protein 180; ARI4B_HUMAN.
詳細(xì)介紹(shào)：
濃 度 1mg/1ml
規(guī) 格(gé) 0.2ml/200μg
抗體來源(yuán) Rabbit
克(kè)隆類(lèi)型 polyclonal
交(jiāo)叉反應 Human, Mouse, Rat, Chicken, Dog, Cow, Horse
產品(pǐn)類(lèi)型(xíng) 一抗
研(yán)究領域(yù) 腫(zhǒng)瘤 細胞生(shēng)物 免疫(yì)學 染(rǎn)色(sè)質和(hé)核信(xìn)號(hào) 細胞(bāo)類型標誌(zhì)物(wù)
性(xìng) 狀 Lyophilized or Liquid
免(miǎn) 疫(yì) 原 KLH conjugated synthetic peptide derived from human BRCAA1
亞(yà) 型 IgG
純(chún)化方(fāng)法 affinity purified by Protein A
儲(chǔ) 存(cún) 液(yè) 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產品應(yīng)用(yòng) ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蠟(là)切(qiē)片(piàn)需做(zuò)抗原(yuán)修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條(tiáo)件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相(xiāng)關(guān)資(zī)料(liào)：
產品介紹(shào) This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008].
Function : Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
Subunit : Component of a Sin3A corepressor complex consisting of SIN3A, SAP130, SUDS3/SAP45, SAP180, HDAC1 and HDAC2.
Subcellular Location : Nucleus (By similarity). Cytoplasm. Note=Cytoplasmic in breast cancer cells.
Tissue Specificity : Highly expressed in the testis and in breast, lung, colon, pancreatic and ovarian cancers. Expressed at low levels in the thymus, prostate and ovary.
Similarity : Contains 1 ARID domain.
Database links : UniProtKB/Swiss-Prot: Q4LE39.2
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