產品編(biān)號(hào)：Y3246
英文(wén)名(míng)稱：8-Methoxypsoralen
CAS號 298-81-7  
分(fēn)析(xī)標(biāo)準品(pǐn),≥98%
分(fēn)子式(shì) C12H8O4 分子量216.19

基(jī)本信(xìn)息(xī):

密度(dù) 1.368
熔點(diǎn) 143-148°C
溶解性 Soluble in acetone, ethanol (slight), acetic acid, and chloroform (50 mg/ml). Insoluble in water.
描述(shù) 
別(bié)名 花(huā)椒(jiāo)毒素;甲氧基補(bǔ)骨(gǔ)脂素;甲氧沙(shā)林;8-MOP;9-甲(jiǎ)氧(yǎng)基呋喃(nán)並[3,2-g][1]苯(běn)並(bìng)吡(pǐ)喃(nán)-7-酮;花(huā)椒(jiāo)毒內酯;8-MOP;Ammoidin;Methoxsalen;Xanthotoxin;9-Methoxyfuro[3,2-g][1]benzopyran-7-one
生化(huà)機(jī)理 8-Methoxypsoralen is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450). As a member of the foranocoumarins, 8-Methoxypsoralen has shown more potency than 5-MOP, 5-OH-P , DH-8-MOP and psoralen in the inhibiton of CYP2B1 (cytochrome P-450 2B1). 8-Methoxypsoralen has been shown to completely inhibit the metabolism of nicotine in vitro. The compound has been observed to inhibit the metabolism of theophylline,caffeine,hexobarbital and phenytoin.
應用(yòng) A potent suicide inhibitor of cytochrome P-450.